cefuroxime sodium

Clinical research of cefuroxime sodium for injection

注射用头孢呋辛钠临床研究

The stability study of the compatibility of cefuroxime sodium and fructose injection

头孢呋辛钠与果糖注射液配伍的稳定性考察

The Stability of Cefuroxime Sodium and Vitamin C in 5% GS Transfusion

头孢呋辛钠在输液中与维生素C配伍的稳定性考察

Conclusion: cefuroxime sodium could combine with tinidazole and glucose injection.

结论：头孢呋辛钠可与替硝唑葡萄糖注射液配伍应用。

Objective To study the mechanism of aminolysis and degradation product of cefuroxime sodium.

目的研究头孢呋辛钠的氨解机理和产物。

CONCLUSIONS Cefuroxime sodium injection can effectively treat lower respiratory infection and urinary tract infection caused by sensitive pathogenic bacteria, and furthermore, the occurrence rate of side-effect is low, which similar to the import product Zinacef.

结论注射用头孢呋辛钠对临床常见的致病菌引起的下呼吸道感染、泌尿系感染，临床疗效较好且不良反应发生率低，与进口西力欣相近。

Clinical Observation of Therapeutic Effect of Cefuroxime Sodium on Respiratory Tract Infections in 30 Cases

头孢呋辛钠治疗呼吸系统感染30例临床疗效观察

The adverse reaction was evaluated in 86 cases of cefuroxime sodium group and 79 cases of Zinacef group. The adverse drug reaction rates were 10.5% ( 9/ 86) and 15.2% ( 12/ 79), respectively.

两组安全性评价分别为86例及79例，不良反应发生率分别为10.5%（9/86）与15.2%（12/79）。

Results: There were no evident changes in appearance and content, and pH was stable except cefuroxime sodium mixed with puerarin injection.

结果：头孢呋辛钠与葛根素配伍后含量及外观稳定，但pH值有变化：与酚磺乙胺、穿琥宁、氨甲苯酸配伍后含量、外观、pH值均稳定。

Biological Equivalent Effect of Cefuroxime Sodium Injection

注射用头孢呋辛钠生物等效性研究

METHODS: 30 cases of respiratory tract infections were enrolled in this study. Cefuroxime sodium was given in a dose of 1.5g iv bid for 7~ 10 days and the therapeutic effect and bacteria clearance rate were observed.

方法：选择呼吸系统感染性疾病患者30例，给予头孢呋辛钠每次15g，静脉滴注，每日2次，7天～10天为1疗程，并观察其临床疗效及细菌消除情况。

OBJECTIVE: To evaluate the clinical efficacy and safty of cefuroxime sodium.

为了进一步评价头孢呋辛钠治疗细菌性感染的安全性，有效性及药物不良反应。

The Clinical Effects of Cefuroxime Sodium on Acute Bacterial Infectious Diseases

头孢呋辛钠治疗细菌性感染的疗效对照

Objective To improve the clarity and color of cefuroxime sodium for injection.

目的研究注射用头孢呋辛钠的澄清度和颜色。

Through the study in this paper, a new type of coupling crystallization technology was developed to prepare Cefuroxime Sodium, which are more stable and of high quality.

通过本论文的研究工作，开发了一种新型耦合结晶工艺，制备出性质稳定的头孢呋辛钠，并对其耦合结晶过程的工艺进行了系统工程的研究，实现了该新工艺的全程优化。

Study on Stability of Compatibility of Cefuroxime Sodium Injection with 6 Drugs

头孢呋辛钠注射液与6种药物配伍稳定性研究

Objective To observe the therapeutic effect of domestic cefuroxime sodium on respiratory tract infections.

目的观察国产头孢呋辛钠对呼吸系统感染性疾病的治疗效果。

Objective: To develop a kind of developing system of HPTLC for direct analyzing the colored impurity of cefuroxime sodium.

目的：探讨一种新的适合的HPTLC展开系统以直观分析头孢呋辛钠的有色杂质。

Objective: To study the safety of cefuroxime sodium for injection.

目的：评价注射用头孢呋辛钠的给药安全性。

Methods: 40 patients were recruited and divided into 2 group by random and mono blind methods, and treated with Cefuroxime sodium and Zinacef respectively.

方法：急性细菌感染性疾病患者40例，进行前瞻性多中心随机单盲平行对照试验，分别给予国产与进口头孢呋辛钠治疗。

Objective : To study the stabilities of cefuroxime sodium for injection.

目的: 探讨注射用头孢呋辛钠的稳定性.

Determination of Cefuroxime Sodium for Injection by HPCE

注射用头孢呋辛钠的HPCE测定

ConclusionStep-down Cefuroxime Sodium and Cefixime Granules treatment in middle-serious bacterial infection has superiority in cost-effect analysis.

结论：头孢呋辛钠、头孢克肟序贯治疗儿科中度感染有明显成本效益优势。

Objective: To study the stabilities of cefuroxime sodium for injection.

目的：探讨注射用头孢呋辛钠的稳定性。

Determination of Bacterial Endotoxins in Cefuroxime Sodium for Injection

注射用头孢呋辛钠细菌内毒素的检测

HPCE ( high performance capillary electrophoresis ) method for determination of cefuroxime sodium for injection was established.

建立高效毛细管 电泳 法测定注射用头孢呋辛钠的含量.

Results The mixture of cefuroxime sodium injection with aminophylline resulted in significant drop in pH and the contents of cefuroxime sodium;

结果头孢呋辛钠注射液与氨茶碱注射液配伍后pH值及含量显著下降；

So we determined the physicochemical index for raw material selection of cefuroxime sodium reference standard.

据此确定了头孢呋辛钠标准物质原料选择的理化指标。

Cefuroxime Sodium is one of the second generation cepHalosporin, which is a market leader drug.

头孢呋辛钠是第二代头孢菌素类药物市场的领军产品。

Studies on Technics of Preparing Cefuroxime Sodium and Cefuroxime Axetil

头孢呋辛钠和头孢呋辛酯制备工艺的研究